Normal pressure hydrocephalus: Diagnostic and predictive evaluation

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Normal pressure hydrocephalus: Diagnostic and predictive evaluationon

In typical cases, normal pressure hydrocephalus (NPH) manifests itself with the triad of gait disturbance, which begins first, followed by mental deterioration and urinary incontinence associated with ventriculomegaly (on CT or MRI) and normal cerebrospinal fluid (CSF) pressure. These cases present minor diagnostic difficulties and are the most likely to improve after shunting. Problems arise w...

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Updates in diagnostic evaluation and management of Normal pressure hydrocephalus

In the three cases of Normal pressure hydrocephalus (NPH) described by Adams and Hakim in the sixties 1, two secondary after head trauma and one idiopathic, all were clinically improved by the removal of cerebrospinal fluid. 40 years after the initial findings, it is beyond question, that NPH remains an important treatable syndrome of dementia and of gait disorder associated with an enlargement...

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Normal pressure hydrocephalus.

Normal pressure hydrocephalus (NPH) is a reversible disorder characterized by gait impairment, subcortical dementia, and urinary urgency and incontinence associated with impaired cerebrospinal fluid circulation and ventriculomegaly. Treatment with shunt surgery is most likely to increase mobility, and may also improve dementia and urinary symptoms. An international, independent study group rece...

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Idiopathic Normal Pressure Hydrocephalus

Idiopathic normal pressure hydrocephalus (iNPH) is a potentially reversible neurodegenerative disease commonly characterized by a triad of dementia, gait, and urinary disturbance. Advancements in diagnosis and treatment have aided in properly identifying and improving symptoms in patients. However, a large proportion of iNPH patients remain either undiagnosed or misdiagnosed. Using PubMed searc...

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Normal pressure hydrocephalus

Results: Forty-one patients underwent an invasive diagnostic procedure for evaluation of suspected NPH; 13 ultimately received shunts, representing an incidence of 1.19/100,000/year. The incidence of sustained definite improvements at 3 years after shunting was only 0.36/ 100,000/year. Definite gait improvement was documented in 75% at 3–6 months after shunt placement, although it dropped to 50...

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ژورنال

عنوان ژورنال: Dementia & Neuropsychologia

سال: 2009

ISSN: 1980-5764

DOI: 10.1590/s1980-57642009dn30100003